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goldenseal marijuana

GOLDENSEAL

Chinese Goldenseal, Eye Balm, Eye Root, Fard Inolien, Framboise de Terre, Goldenroot, Goldsiegel, Ground Raspberry, Hydraste, Hydraste du Canada, Hydrastis canadensis, Indian Dye, Indian Plant, Indian Turmeric, Jaundice Root, Orange Root, Racine Г la Jaunisse, Racine Orange, Sceau D’Or, Sello de Oro, Turmeric Root, Warnera, Wild Curcuma, Yellow Indian Paint, Yellow Paint, Yellow Puccoon, Yellow Root.

  • Overview
  • Uses
  • Side Effects
  • Interactions
  • Dosing

Overview Information

Goldenseal is an herb. The dried root is used to make medicine.

Goldenseal is used for many conditions, but so far, there isn’t enough scientific evidence to determine whether or not it is effective for any of them.

We do know that goldenseal isn’t effective for its most famous use, masking illegal drugs in the urine. Despite rumors to the contrary, goldenseal won’t cause false-negative results for marijuana, cocaine, amphetamines or numerous other illegal drugs. Interestingly, the idea of using goldenseal to alter drug screen results came from the novel Stringtown on the Pike, by the pharmacist John Uri Lloyd. However, in this book, goldenseal caused a false-positive for strychnine poisoning, not illegal drugs.

Goldenseal is also used for the common cold and other upper respiratory tract infections, as well as stuffy nose and hay fever. Some people use goldenseal for digestive disorders including stomach pain and swelling (gastritis), peptic ulcers, colitis, diarrhea, constipation, hemorrhoids, and intestinal gas.

Goldenseal is used for urinary tract infections (UTIs), internal bleeding, bleeding after childbirth, liver disorders, cancer, chronic fatigue syndrome (CFS), jaundice, gonorrhea, fever, pneumonia, malaria, whooping cough, and an eating disorder called anorexia.

Women use goldenseal for vaginal pain and swelling and menstrual period problems.

Goldenseal is applied to the skin for rashes, ulcers, wound infections, itching, eczema, acne, dandruff, ringworm, herpes blisters, and cold sores. It is used as a mouthwash for sore gums and mouth.

Some people use goldenseal as an eyewash for eye inflammation and eye infections called conjunctivitis, or “pink eye.”

Goldenseal is used in the ears for ringing, earache, and deafness.

Goldenseal is commonly found in the deep woods from Vermont to Arkansas and received its name from the golden-yellow scars on the base of the stem. When the stem is broken, the scar resembles a gold wax letter seal.

How does it work?

Goldenseal contains the chemical berberine, which might have effects against bacteria and fungi. For example, it can prevent the bacteria Escherichia coli (E. coli) from binding to urinary tract walls. Berberine also has properties that can lower blood pressure and improve irregular heartbeats. In addition, early research suggests that berberine can lower blood sugar and “bad” low-density lipoprotein (LDL) cholesterol.

Many of the important chemicals in goldenseal are poorly absorbed when taken by mouth and might not reach the concentrations needed to have significant effects in humans. So, it is unknown whether goldenseal has the same benefits as berberine.

Uses & Effectiveness ?

Possibly Ineffective for

  • Masking illegal drugs in urine tests. Goldenseal is often promoted to mask illicit drugs in the urine, but taking goldenseal by mouth does not seem to cause a false-negative result on drug tests for amphetamines, barbiturates, benzodiazepines, cocaine, opiates, phencyclidine, and tetrahydrocannabinol (THC). Drinking one gallon of water with goldenseal does not increase the number of false negatives over water alone.

Insufficient Evidence for

  • Urinary tract infections (UTIs).
  • Hemorrhoids.
  • Stomach upset.
  • Loss of appetite (anorexia).
  • Stomach ulcers.
  • Colitis.
  • Menstrual irregularities.
  • Chronic fatigue syndrome (CFS).
  • Conjunctivitis.
  • Nasal congestion.
  • Hay fever.
  • Other conditions.

More evidence is needed to rate goldenseal for these uses.

Side Effects & Safety

Goldenseal is POSSIBLY SAFE for most adults when taken by mouth as a single dose. There is not enough reliable information to know if goldenseal is safe for long-term use.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Using goldenseal during pregnancy or breast-feeding is LIKELY UNSAFE for the infant. A hazardous chemical in goldenseal can cross the placenta and can also find its way into breast milk. Brain damage (kernicterus) has developed in newborn infants exposed to goldenseal. Do not use goldenseal during pregnancy or breast-feeding.

Children: Don’t use goldenseal in newborn babies. It is LIKELY UNSAFE for them. It might cause brain damage (kernicterus).

Interactions ?

Moderate Interaction

Be cautious with this combination

Cyclosporine (Neoral, Sandimmune) interacts with GOLDENSEAL

The body breaks down cyclosporine (Neoral, Sandimmune) to get rid of it. Goldenseal might decrease how fast the body breaks down cyclosporine (Neoral, Sandimmune). This might cause there to be too much cyclosporine (Neoral, Sandimmune) in the body and potentially cause side effects.

Digoxin (Lanoxin) interacts with GOLDENSEAL

Taking goldenseal with digoxin (Lanoxin) might cause a very slight increase in digoxin (Lanoxin) levels in the body. But this does not seem to be an important interaction.

Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates) interacts with GOLDENSEAL

Some medications are changed and broken down by the liver. Goldenseal might decrease how quickly the liver breaks down some medications. Taking goldenseal along with some medications that are changed by the liver can increase the effects and side effects of your medication. Before taking goldenseal talk to your healthcare provider if you take any medications that are changed by the liver.

Some medications that are changed by the liver include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with GOLDENSEAL

Some medications are changed and broken down by the liver.

Goldenseal might decrease how quickly the liver breaks down some medications. Taking goldenseal along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking goldenseal, talk to your healthcare provider if you are taking any medications that are changed by the liver.

Some medications changed by the liver include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and many others.

Medications moved by pumps in cells (P-Glycoprotein Substrates) interacts with GOLDENSEAL

Some medications are moved by pumps in cells. Goldenseal might make these pumps less active and increase how much of some medications get absorbed by the body. This might increase the amount of some medications in the body, which could lead to more side effects. But there is not enough information to know if this is a big concern.

Some medications that are moved by these pumps include etoposide, paclitaxel, vinblastine, vincristine, vindesine, ketoconazole, itraconazole, amprenavir, indinavir, nelfinavir, saquinavir, cimetidine, ranitidine, diltiazem, verapamil, corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others.

Dosing

The appropriate dose of goldenseal depends on several factors such as the user’s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for goldenseal. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Learn more about Goldenseal uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Goldenseal

THC Detox: 3 Ways to Pass a Cannabis Drug Test

Of all the intoxicants in the world, THC is one of the stickiest; it stays in the system for a long time. This is inconvenient for people who take mandated drug tests, or for those who live in places that perform roadside drug testing. Do you need to pass a drug test and want to flush cannabis out of your system? Check out these 3 detoxing methods.

Despite the fact that the world is becoming ever more cannabis-friendly, there are still some logistical hurdles for cannabis users. In some countries, it is common practice for certain professionals to take a mandatory drug test. Roadside drug testing has also become more prevalent over the years.

The classification of cannabis is still debated, and despite progress in the legalization movement, it is still considered a dangerous intoxicant by most governments. In fact, even in places where cannabis is legal, it is still taboo to drive under the influence or to test positive in the professional context. Naturally, this situation can make a patient or recreational customer’s cannabis experience difficult and less than ideal – especially if they were to test positive for cannabis.

How long does THC stay in your system?

When drug tests are performed, they are virtually never testing for THC. Rather, they are testing for a metabolite of THC that is produced in the liver: In THC’s case that is THC-COOH. This THC metabolite lives in urine and blood for much longer than THC itself. The evidence reported a THC-COOH plasma-elimination half-life of up to 12.6 d in a chronic cannabis user, which means that every 13 days, whatever amount of it present in your body will decrease by 50%.

According to a factsheet issued by the National Drug Court Institute, one-time (or very sparse) consumers can eliminate cannabis in a matter of days. If consumed more frequently, it can take longer for the body to flush out the accumulated cannabinoids: at a cut-off concentration of 50 ng/ml, an occasional user urine sample wouldn’t contain detectable cannabinoid metabolites levels 3-4 days after smoking, the detection period being up to 10 days for a chronic user.

Cannabis detection is influenced by many factors such as the potency of the cannabis itself, the frequency with which it is used and the state that your physical body is in (metabolism, body fat, and amount of physical exercise).

Your body itself is a prime factor in the equation, as THC is stored in fat cells. These fat cells progressively release THC, along with other cannabinoids, into your blood. Fat cells are a prime factor in gaining or losing weight. Although not confirmed by scientific studied, it might be theorized that when more fat cells are present in the body, more THC can be stored in that body.

How to pass a drug test in 2 days

To succeed in flushing cannabis out of your system in time for a test also depends on what kind of drug test is being administered. Most employer mandated drug tests are urine tests, whereas most roadside drug tests are saliva swabs.

For infrequent cannabis users, cannabis can be detected in urine 3 to 4 days after consumption with most urine testing facilities. Saliva swabs detect THC and its metabolites for up to 30 hours after use at most.

This window grows increasingly large the more you consume, except in the case of saliva testing, in which the frequency with which you use doesn’t really matter. This is why the best way to avoid testing positive on a drug test is to abstain from use. That’s an unlikely and unwanted solution for many consumers, so good timing and preparation are the next best solutions.

Related post

Cannabis DNA Tests: Do They Work & Are They Worth It?

There’s no sure-fire way to detox from cannabis and its metabolites rapidly, regardless of what certain detox products will tell you. There are too many factors that play a role, and most of those factors vary from person to person. However, there are ways to prepare for a drug test and reduce the chances of testing positive.

1. Detox with diet: Consume detoxifying foods and drinks

This one’s tricky. Detoxing with foods is a debatable topic altogether. Detox diets are popular, and generally have two goals: To help you lose weight, and to help you release toxins. The first goal is not the focus of this article, but the second one is.

Do detoxifying foods help you release toxins? That hasn’t been proven yet. Hopefully more research will emerge, since so many people follow these diets. Anecdotal reports do suggest some dietary changes that might help you though:

Increase your fluids intake

Fluids help dilute metabolites in urine. Metabolites are a chemical produced by the body from another chemical taken into the body, THC COOH in the case of delta-9 THC. Drug tests are designed to measure a certain amount of metabolites, and under the specified threshold, results are considered negative. This means it is not necessary to eliminate every single trace of those metabolites to pass a drug test.

However, drinking high amounts of water can result in urine with low levels of creatinine. In drug testing, urine samples should be tested for creatinine, and if creatinine is below a certain threshold (less than 4.0 mmol/L), negative results may not be valid. Many labs specialized in drug testing consider this an obvious attempt at diluting one’s urine, and it has been known to be flagged as “suspicious” (and could result in a positive test, or an invalid test result).

An alternative would be a drink that provides other elements besides its fluid nature; for instance, a natural detox drink such as cranberry juice, or green tea. If you are taking the non-organic path, several energy drinks contain minerals and/or electrolytes, which can make your urine a more ‘electrically conducting solution’.

Focus on fruits, vegetables and healthy beverages

Carbohydrates and fat are two elements found in many, many foods. For the most part, if you consume processed foods, it is nearly impossible to avoid them. In the case of detox, the more you replace processed food with healthier items such as vegetables or fruits, the more chances you have to detox faster. It’s also worth noting that fruits and vegetables are full of water, helping you with the first suggestion; hydrate yourself!

High quantities of fat in your digestive system can slow down its ability to detox. THC is fat soluble, which could suggest that increasing fat contents can trigger a brand new lifecycle for the cannabinoid.

Lemon juice / lemon water

Everybody knows a health-conscious person who drinks some lemon juice mixed with warm water (lemon water) in the mornings. This is because lemon juice increases metabolism, especially with respect to the way that the body metabolises lipids (fats) – which is exactly where cannabinoids are stored in the body. If you’ve got notice for a drug test, start consuming lemon juice in the mornings as soon as possible.

Cranberry juice

Naturopaths and herbalists often prescribe cranberry juice as a detoxification method, although there’s little scientific evidence to support this. This suggestion mainly rests on anecdotal evidence of success when it comes to THC detox. In any case, the consumption of a cranberry juice beverage lowered the number of clinical urinary tract infection (UTI) episodes in women with a recent history of UTI ; this is the main reason that cranberry juice is used in naturopathic practice.

Be warned: drinking cranberry juice makes your pee turn pink! So try not to consume cranberry juice the day before the drug test, or it might otherwise be very obvious that you’ve tried to detox.

Green tea

When looking for ways to detox from THC, green tea is an option that comes up a lot. It has antioxidant qualities and is said to be very good at flushing the system from contaminants.

However, you would have to consume a lot of green tea to flush THC out of your body. One could consider consuming green tea in tablet as opposed to a green tea beverage, suggesting tablets may be an effective way to enhance plasma antioxidant capacity by green tea, but it’s best not to use it as your final resort option. It’s more of a complementary tool.

Coffee

The active ingredient in those little black beans we all love to consume is caffeine, a natural diuretic. This basically means that it opens the floodgates when it comes to urine. Consuming coffee with large amounts of water and electrolytes can help to pass more liquid from the body, and hopefully that liquid contains a lot of the THC metabolites that have been trapped in your body.

And in addition to the above-mentioned suggestions, certain other detoxifying foods such as greens, garlic, and cilantro, may help as well.

2. Sweat detox: Can you sweat out THC?

Many believe that you can detoxify your system through your sweat. The skin is sometimes likened to the third kidney, especially by practitioners of natural medicine. This is because despite it going on more or less without our conscious knowledge, the skin is one of the biggest excretory organs in the whole body. This is what the principle of the sweat detox rests on. However, there are conflicting beliefs about this method of detox, with some scientists suggesting that detox through sweating is a myth.

If you want to give it a try though, participating in cardiovascular activities such as running, jogging or walking naturally helps to increase sweat production. On top of this, cardiovascular activities also help to burn fat cells, which are the number one place for THC molecules to park themselves. Alternatively, you could try spending time in a sauna to encourage sweating – although research has yet to confirm that suggestion (and what a lovely study that would be!).

3. Only true way to detox: Take a tolerance break from cannabis

Sleeping is another way your body detoxes naturally on a daily basis. Being anxious and stressed, on the other hand, slows down your body’s detoxing efforts. If you can get full night’s sleep and relax, you’re in a much better position to give your body all the tools it needs to detox naturally. You can try activities such as reading or yoga which may help you relax enough to get a restful sleep.

And finally, there’s that truth that many cannabis consumers don’t want to hear: stop consuming cannabis the moment you are notified of a drug test. A tolerance break truly is the most natural form of THC detox. Plus, you’ll be surprised how much your body may benefit from such a detox. But more importantly, giving your body the time to naturally shed any THC in the system is the best way of passing a drug test.

Be careful of store-bought “detox” products

It’s worth a word of warning about some of the detox products that may be marketed to you as a result of your Google search for the important question of THC detoxification. Yes – products exist that are made for this kind of circumstance, whereby supposedly the product will detox you just enough and for just long enough for you to pass a drug test. Most, if not all of them, are not formulated on the back of any scientific evidence, and they can even be dangerous.

These products are not fool-proof, and may result in a failed drug test or even in some adverse symptoms. So be mindful of that before trying any detox products.

There are also home drug testing kits that you can purchase to know “where you’re at” before taking the official drug test. This is highly recommended, because even though they’re not the real deal, you at least have an idea of the potential outcome before you take the test.

Do you know how to flush cannabis out of your system? There is no sure-fire way to do it, but there are tricks to help your body detox. Read more here.